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A rare-cutter enzyme is a restriction enzyme with a recognition sequence which occurs only rarely in a genome. An example is NotI, which cuts after the first GC of a 5'-GCGGCCGC-3' sequence; restriction enzymes with seven and eight base pair recognition sequences are often also called rare-cutter enzymes (six bp recognition sequences are much more common). For example, rare-cutter enzymes with 7-nucleotide recognition sites cut once every 47 bp (16,384 bp), and those with 8-nucleotide recognition sites cut every 48 bp (65,536 bp) respectively. They are used in top-down mapping to cut a chromosome into chunks of these sizes on average. ==External links== *(Bio-Medicine.com's definition ) * Citation: Genomes by T.A. Brown 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Rare-cutter enzyme」の詳細全文を読む スポンサード リンク
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